Dr. Çimen Karasu is a professor in Department in Medical Pharmacology, Gazi University Faculty of Medicine, Ankara, Turkey.

Prof. Karasu obtained her PhD in 1992 from the University of Ankara, Faculty of Pharmacy, and then worked in the University of London, Queen Mary & Westfield College-Basic Medical Sciences, and in William Harvey Research Institute, London. Researching on the cellular stress signaling associated with metabolic disease complications at Ankara University, Prof. Karasu was subsequently enrolled in Gazi University Faculty of Medicine, where she established the “Cellular Stress Response & Signal Transduction Research Laboratory” in 2002.

Prof. Karasu works on cellular mechanisms of aging and age-related metabolic diseases like diabetes, insulin resistance, obesity and complications. The discovery of new preventive/therapeutic agents against neurodegenerative disease like Alzheimer’s, a complication of metabolic diseases characterized by oxidative stress and carbonyl stress, is the main research area of her laboratory. Prof. Karasu interested in the identifying of bioactive molecules for maintaining cellular redox homeostasis. 

Member of the Management Commitee in EU COST Projects

• Personalized Nutrition in Aging Society: Redox Control of Major Age-Related Diseases, COST Action CA16112.
• EU-ROS. Reactive Oxygen Species, COST Action BM1203.
• Chemistry of nonenzymatic protein modification – modulation of protein structure and function, COST Action CM1001.
• Lipid peroxidation associated disorders LPO, COST Action B35.

Coordination of the Latest Research Projects

• “Near-infrared-responsive Ce-Bi@ZIF-8 hybrid nanocomposite for treatment of amyloid-β (Aβ) neurotoxicity: A rational road map against Alzheimer’s disease”. Turkey-TUBITAK and Iran-MSRT, 121R003.
• “Targeting cannabinoid receptor signalling in inflammatory neurodegeneration: a potential role for redox-mediated pathways”. Turkey-TUBITAK and Mexico-CONACYT, No: 315S088.
• “Targeting molecular pathways of glycolipotoxicity by a novel carboxymethylated mercaptotriazinoindole inhibitor of Aldo-Keto reductase AKR1B1 in diabetes, inflammation  and age-related neurodegeneration”. Turkey-TUBITAK and SLOVAK-SAS, 215S197.
• “The role of oxidative stress in apoptosis and dysfunction of pancreatic beta cells: The potential protective effect of novel pyridoindole antioxidants”. Turkey-TUBITAK and SLOVAK-SAS, 108S239.

Major Awards 

• The Best Scientific Collaberation with the Rangsit University, from Faculty of Oriental Medicine, Bangkok, (2010).
• The Best Scientific Collaberation in Natural Sciences, from Institute of Experimentaal Pharmacology & Toxicology-SAS for award of Slovak Academy of Sciences, (2009).

• Novelty Project Lieder” from Scientific and Technological Research Council of Turkey (TUBITAK), (2006).
• Award for the best medical publication from Servier Drug Company, (2005), (Mol Vis. 2005 Jan 19;11:56-65).
• Grant for Postdoctoral Fellowship, from The William Harvey Research Institute, UCL, London, (1993)
• Grant for Research on Evening Primrose Oil and Vitamin E, SCOTIA Pharmaceuticals, United Kingdom (1994).
• Grant for Research in University of London, ONO Pharmaceuticals-Japanese (1993).

Prof. Karasu involved some of the international scientific actions as “Why we Age Study”, “Life Long-Health on the Aging and Age-Related Disease” She is also founder and executive leader of “Preventive, Regenerative, Anti-Aging Medicine Society-Turkey www.antiaging.org.tr”, “The Antioxidants in Diabetes-induced Complications (ADIC) Study Group (PubMed)”, and the both companies as LongAgeHealth and Farmasens Biotech Co., Turkey.

• European Society of Preventive, Regenerative and Anti-Aging Medicine (ESAAM) – Member of the Scientific Board (2006-2012).
• Member of 3rd WOCPM Consensus (World Council for Preventive, Regenerative and Anti-Aging Medicine, [email protected]
• The World Anti-Aging Academy of Medicine (WAAAM) www.waaam.org/advisory-board.
• The World Federation & World Virtual Institute of Preventive & Regenerative Medicine” (PYRAMED-REGMED).
• SECLARM, Swiss European Congress of Longevity, Aesthetic & Regenerative Medicine,

Publications

120 peer reviewed, 3 patents.

Invited lectures

He has been an invited speaker in over 100 academic conferences, over half of which he co-organized and/or co-chaired.